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Question

What factors influence the affinity of hemoglobin for oxygen?


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Solution

Hemoglobin:

The pigment in the blood is responsible to carry oxygen to all cells of the body is known as hemoglobin.

Factors influencing the affinity of hemoglobin for oxygen:

  1. pH: The pH is directly proportional to O2 binding.
  2. pCO2: The pressure of CO2 is inversely proportional to O2 binding.
  3. Absence of unusual hemoglobin species.
  4. Temperature: Temperature is inversely proportional to O2 binding.
  5. Concentration of 2, 3-DPG: The concentration of 2, 3-DPG is inversely proportional to O2 binding.


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