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Question

What forms the juxtaglomerular apparatus?


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Solution

Juxtaglomerular Apparatus:

  1. As the name suggests, it is an apparatus located near the glomerulus of the kidney's nephron.
  2. It is formed by three structures: macula dense cells of the tubule, juxtaglomerular or granular cells of the afferent arteriole, and extraglomerular mesangial cells.
  3. Juxtaglomerular or granular cells surroundd the afferent arteriole.
  4. The macula dense cells lie adjacent to Juxtaglomerular cells.
  5. Extraglomerular mesangial cells have phagocytic and contractile properties and they will influence capillary filtration.
  6. The main function of the juxtaglomerular apparatus is the secretion of renin in response to decreased renal blood pressure or blood flow.

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