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Question

What governs cell proliferation in normal tissues?


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Solution

Cell proliferation:

  1. The process by which cells have the ability to grow and divide and replenish the lost cells is referred to as cell proliferation.
  2. This is a very highly regulated activity in normal, healthy tissue.
  3. Cell proliferation is regulated by the growth factors that are responsible for transducing signals that promote entry into the cell cycle.
  4. Cell proliferation is regulated by the suppressor proteins, majorly p53 which plays a major role in multiple cell cycle checkpoints.
  5. The various survival processes are capable of suppressing the process of apoptosis. (programmed cell death).

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