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Question

What happens to ammonia in reductive amination?


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Solution

Ammonia:

  1. Ammonia is a nitrogen and hydrogen chemical with the formula NH3.
  2. Ammonia is a naturally occurring gas that is also created by human activities.
  3. It is a vital supplier of nitrogen, which plants and animals require.
  4. Ammonia is a colorless gas with a strong odor.

Amination:

  1. Amination is the process by which we may add an amine group to a molecule.
  2. Amination processes include reductive amination and transamination.

Reductive amination:

  1. The conversion of an aldehyde or ketone into an amine via an intermediary imine is known as reductive amination.
  2. This reaction is regarded as the most impressive method of synthesizing complex amines, and it produces the vast majority of amines used in the pharmaceutical sector.
  3. Ammonia interacts with glutamic acid to generate -ketoglutaric acid.

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