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Question

What happens to the nucleolus during mitosis?


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Solution

Mitosis:

  1. It is the process through which a cell copies and then segregates its chromosomes, forming two identical nuclei in preparation for cell division.
  2. It is often followed by the equal division of the cell's contents into two daughter cells with identical genomes.
  3. The nucleolus is a spherical structure located in the nucleus of cells that produces and assembles the cell's ribosomes.
  4. The nucleolus and nuclear envelope both dissolve at the conclusion of the prophase during mitosis.
  5. The nuclear envelope disintegrates early in mitosis, releasing a significant percentage of its contents into the cytoplasm.
  6. The nucleolus disassembles at the start of mitosis.
  7. The end of the prophase is the point in mitosis when the nuclear envelope breaks down.
  8. At this time, the nuclear envelope's remnants effectively exist as vesicles.
  9. The chromosomes condense in addition to the collapse of the nuclear membrane and disintegration of the nucleolus.
  10. Once mitosis is complete, chromosomes reorganise and nuclear envelopes reunite around the divided daughter chromosomes, generating two new nuclei.
  11. Dephosphorylation of rRNA transcription factors happens when the chromosomes decondense.
  12. The nucleolus may then begin its activity because RNA transcription has restarted.

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