Question

What happens when the ${\mathrm{O}}_2$ hb dissociation curve shifts?

Answer 1

Dissociation of the curve:

1. The ${\mathrm{O}}_2$-Hb dissociation curve describes the efficiency of oxy-Hb (oxyhemoglobin) releasing oxygen to tissue cells in the phenomenon of internal respiration, showing a distinctive sigmoid shape.
2. When the dissociation curve shifts to the right, it results in the Bohr effect, wherein lesser haemoglobin (Hb) saturation takes place.
3. Here, more oxygen is liberated from oxyhemoglobin.
4. When the dissociation curve shifts to the left (less likely), it is referred to as the Haldane effect.
5. Here, more haemoglobin saturation takes place while lesser oxygen is released.