Pancreatic secretions are also the main mechanism for neutralizing gastric acid in the small intestine of a body.
When acid reaches the small gut, it stimulates secretin to be discharged, and the effect of this hormone is to stimulate the secretion of lots of bicarbonate.
Secretin and cholecystokinin (CCK) are the two hormones that stimulate pancreatic secretion.
Secretin stimulates the secretion of water and bicarbonates.
CCK stimulates the secretion of pancreatic enzymes.