Question

What hormone stimulates the release of bicarbonate from the pancreas?

Answer 1

Hormone stimulating the release of bicarbonate from the pancreas:

1. Secretin is the hormone that stimulates the release of bicarbonate from the pancreas.
2. The small intestine secretes 4 types of hormones; cholecystokinin, secretin, gastric inhibitory peptide (GIP) as well as Motilin. While cholecystokinin and secretin are secreted from the three parts of the small intestine, the duodenum, jejunum, and ileum, respectively, GIP, along with motilin, is secreted only from the duodenum and jejunum.
3. Cholecystokinin is produced by "I" cells, "S" cells secrete secretions, GIP is composed of "K" cells, and "M" cells secrete MOV. These hormones are released as a result of various stimuli such as proteins, fats, carbohydrates as well as acids in the intestines.
4. Pancreatic juice is also the main mechanism for neutralizing gastric acid in the body's small intestine. When acid reaches the small intestine, it stimulates the evacuation of secretin, and the effect of this hormone is to stimulate the secretion of more bicarbonate.