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What is a Centromere?
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The centromere is the chromosome region that attaches to a spindle fibre at metaphase of mitosis or meiosis and moves to the spindle pole at anaphase, pulling the rest of the chromosome behind it. Centromere plays an essential role in proper chromosome segregation during mitosis and meiosis in eukaryotic cells. Centromere function includes sister chromatid adhesion and separation, microtubule attachment, chromosome movement, establishment of heterochromatin and mitotic checkpoint control.
The centromere is the chromosome region that attaches to a spindle fibre at metaphase of mitosis or meiosis and moves to the spindle pole at anaphase, pulling the rest of the chromosome behind it. Centromere plays an essential role in proper chromosome segregation during mitosis and meiosis in eukaryotic cells. Centromere function includes sister chromatid adhesion and separation, microtubule attachment, chromosome movement, establishment of heterochromatin and mitotic checkpoint control.
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