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Question

What is a restriction fragment length polymorphism (RFLP) ?

A
A sequence of DNA complementary to a mRNA molecule
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B
A variation in length of DNA fragments due to inherited differences in proteins produced
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C
A variation in length of DNA fragments due to inherited differences in highly repetitive DNA
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D
A variation in length of DNA fragments due to random differences in highly repetitive DNA
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Solution

The correct option is C A variation in length of DNA fragments due to inherited differences in highly repetitive DNA
Restriction Fragment Length Polymorphism is a technique that exploits variation in homologous DNA sequences. It refers to a difference between samples of homologous DNA molecules from differing locations of restriction enzyme sites and to a related laboratory technique by which these segments can be illustrated. In RFLP analysis, the DNA sample is broken down into pieces (digested) by restriction enzymes and the resulting fragments are separated according to their length by gel electrophoresis.
So, the correct option is 'A variation in length of DNA fragments due to inherited differences in highly repetitive DNA'.

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