Question

What is an example of a mutation in animals?

Answer 1

Mutation:

1. The change or alteration in the DNA sequences results in changes in the phenotype and genotype of an organism is called a mutation.
2. The change in the DNA is caused due to change in the single base pair of the DNA( point mutation) or exposure to the chemicals that can cause mutations(mutagens).
3. The mutations can occur both in the somatic and germinal cells (sex cells) of the body.
4. Somatic mutation can result in cancer, and germinal mutation can cause genetic disorders such as cystic fibrosis, which can be transmitted from parents to the offspring.
5. Sickle cell anemia is an example of a mutation in animals.
6. It is a point deletion mutation whereby an acidic amino acid residue glutamic acid, is replaced by valine.
7. This leads to the mutation in the beta-globin chain.
8. The red blood cells become sickle-shaped and their oxygen-carrying capacity is reduced.
9. The patient suffers from anemia and associated symtptoms.