Question

What is apoptosis kindly explain with eg.

Answer 1

In multicellular organisms, cells that are no longer needed or are a threat to the organism are destroyed by a tightly regulated cell suicide process known as Apoptosis or Programmed Cell Death. Apoptosis is mediated by proteolytic enzymes called caspases. When a cell is compelled to commit suicide, caspases go into action. They break down the cellular components needed for survival, and they spur production of enzymes known as DNases, which destroy the DNA in the nucleus of the cell. Apoptosis is the form of cell death in which a programmed sequence of events leads to the elimination of cells without releasing harmful substances into the surrounding area. Apoptosis plays a crucial role in developing and maintaining the health of the body by eliminating old cells, unnecessary cells, and unhealthy cells. The human body replaces perhaps one million cells per second. Too little or too much apoptosis can play a role in many diseases. When apoptosis does not work correctly, cells that should be eliminated may persist and become immortal,

for example, in cancer and leukemia. When apoptosis works overly well, it kills too many cells and inflicts grave tissue damage. This is the case in strokes and neurodegenerative disorders such as Alzheimer's, Huntington's, and Parkinson's diseases. Also known as programmed cell death and cell suicide.

Eg: RBC death between 105 to 120 days.
WBC death between 5-21 says.