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What is ECM?


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Solution

ECM:

  1. Living tissues are not just tightly packed cells. Much of a tissue's volume is made up of extracellular space.
  2. This void is filled with a complex meshwork called the extracellular matrix.
  3. The ECM is a dynamic, physiologically active component of all living tissues.
  4. In addition to providing structural support for the cells embedded within a tissue, the extracellular matrix guides their division, growth, and development.
  5. A few key ingredients of the ECM are water, fibrous proteins, and proteoglycans.
  6. The main fibrous proteins that build the ECM are collagens, elastins, and laminins.

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