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Question

What is glomerular filtration? What is the normal filtration force in humans?

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Solution

The first step in the urine formation is the filtration of blood. which is carried out by the glomerulus and is called glomerular filtration. The amount of the filtrate formed by the kidneys per minute is called the glomerular filtration rate (GFR). The net filtration pressure is the outward pressure minus the inward pressure i.eGlomerular(blood) hydrostatic pressure-(Blood colloidal osmotic pressure+Capsular hydrostatic pressure) =55mm Hg - (30 mm HG +15 mmHg) = 10 mm Hg. Therefore the normal filtration force in humans is 10 mm Hg.

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