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What is Lyon's hypothesis?

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Lyon's hypothesis states that the phenotypic effect of the X chromosome is the same in the mammalian female which has two X chromosomes as it is in the male which has only one X chromosome. One out of two X chromosomes in females is inactivated early in embryonic development. It is called as the Barr body. The Barr body is highly condensed and does not have any phenotypic effect.

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