Question

What is meant by denaturation of enzyme?

Answer 1

Denaturation:

1. The altering of a protein's molecular structure is known as denaturation.
2. During denaturation, many of the weak connections and interactions (such as hydrogen bonds) inside a protein molecule that is responsible for the highly ordered structure of the protein in its natural (native) state, are broken.
3. Enzyme denaturation happens when the structure of a protein and its functional group undergo conformational changes, resulting in inactivity.
4. Denatured proteins have a looser, more random structure, and the majority of them are insoluble.
5. Heating, alkaline, acidic, urea, or detergent treatment, as well as forceful shaking, can all be used to denaturize proteins.