The process by which actively dividing cells of meristematic tissue lose their capacity to divide and thus develop into permanent tissue is called differentiation.
Differentiated tissue:
The cells formed as a result of differentiation are called differentiated or permanent cells.
During this process, most of the cells change their structure and lose their cytoplasm.
Cells grow in size and do not undergo any further changes after formation.
Cells develop large intercellular spaces since they are not closely arranged.
The nucleus becomes less prominent.
Vacuoles become large in size and lie in the center.
Cell wall becomes thick and is secondary in nature.