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Question

What is pituitary gland? What is its function ?

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Solution

The Pituitary gland, also known as the hypophysis, is a pea-sized endocrine gland situated at the base of our brain. It is often referred to as the ‘Master Gland’ because it produces some of the important hormones in the body. It is situated in a bony structure called the Pituitary fossa, just below the hypothalamus, close to the optic nerve. The pituitary gland is divided into three parts, also called lobes:

  • Anterior pituitary
  • Intermediate pituitary (Absent in adult human beings)
  • Posterior pituitary

The anterior pituitary is responsible for the synthesis and secretion of several key hormones in the body. These hormones include:

  • Human Growth Hormone (HGH): Responsible for the growth and repair of all cells in the body.
  • Thyroid Stimulating Hormone (TSH): Influences the thyroid gland for the release of thyroxine, its own hormone. TSH is also called Thyrotropin.
  • Adrenocorticotropic Hormone (ACTH): Influences the adrenal gland to release Cortisol or the “stress hormone”. ACTH is also known as corticotropin.
  • Luteinising Hormone (LH) and Follicle-Stimulating Hormone (FSH): Collectively known as Gonadotropins, LH and FSH control the sexual and reproductive characteristics in males and females.
  • Prolactin (PRL): Produces milk in the breast. Though it is present at all times, the secretion is increased during and just after pregnancy.
  • Melanocyte-Stimulating Hormone (MSH): Involved in the stimulation of the production of melanin by skin and hair.

The posterior pituitary is responsible for the storage and secretion of two very important hormones:

  • Antidiuretic Hormone (ADH): Controls the water balance of the body by affecting the reabsorption of water by the kidneys
  • Oxytocin: Controls certain aspects of pregnancy and childbirth such as uterine contraction and production of milk.


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