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Question

What is role of liver in iron homeostasis?


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Solution

Iron homeostasis:

  1. The series of chemical events that maintain human iron homeostasis at the systemic and cellular levels is known as human iron metabolism.
  2. Iron is both required and potentially hazardous to the body.

Role of liver in iron homeostasis:

  1. The liver is the primary site for the generation of proteins that maintain systemic iron balance.
  2. It is a storage site for excess iron.
  3. It is essential for iron mobilization from hepatocytes to the circulation.

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