Question

What is the difference between silent mutation and non sense mutation?

Answer 1

Silent mutation:

A silent mutation is a change in the sequence of nucleotide bases that constitutes DNA strands without a change in amino acids.

Nonsense mutation:

A nonsense mutation is a point mutation that leads to a change of a codon to the stop codon.

Differences between silent and non-sense mutation:

Silent mutation	Nonsense mutation
It does not change the function of the amino acid or proteins.	It creates truncated and mostly non-functional protein.
2. Silent mutations are mutations in which the amino acid sequence is not altered	2. The nonsense mutation changes the amino acid sequence.
3. Example: Laron dwarfism	3. Example: Cystic fibrosis