Question

What is the difference between Gluconeogenesis and Glycogenesis?

Answer 1

Gluconeogenesis:

1. Gluconeogenesis works in the opposite direction of glycolysis, which creates glucose from pyruvate, lactate, and glucogenic amino acids. It’s also known as Neoglucogenesis.
2. It’s a universal pathway found in humans, animals, plants, fungus, and other living species.

Glycogenesis:

1. Glycogenesis can be defined as the process through which glycogen is synthesized and glucose molecules are added to the glycogen chains for storage purposes.
2. In the human body, the process of glycogenesis is activated post the Cori cycle when the body is in a rest period.
3. The process usually occurs in the liver.
4. It is important to note that the process of glycogenesis can also be activated by the peptide hormone insulin in order to respond to relatively high glucose levels in the body.

Gluconeogenesis	Glycogenesis
Gluconeogenesis is the process of the formation of glucose from noncarbohydrate sources,	Glycogenesis is the process of the formation of glycogen from glucose.
2. Glycogenolysis is the production of glucose 6-phosphate by splitting a glucose monomer from glycogen by adding an inorganic phosphate.	2. Gluconeogenesis is the metabolic process by which glucose is formed from non-carbohydrate precursors in the liver.