What is the difference between Glycogenesis and Glycogenolysis?

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Solution

Glycogenesis:
The process of the production of glycogen from glucose is termed glycogenesis.
Glycogenolysis:that
The metabolic degradation of glycogen to glucose is termed glycogenolysis.
S.no Glycogenesis Glycogenolysis
1. The process takes place in the cells of muscle and liver. The process takes place in the cells of the liver and muscle in reaction to neural and hormonal signals
2. There is a requirement of 1 ATP (adenosine triphosphate) for any unit of glucose supplemented into the polymeric branched composition of glycogen at the time of glycogen synthesis. It generates much more energy.
3. Glycogenesis decreases the blood sugar level to normal. Glycogenolysis increases the blood sugar level.
4. Inhibited by glucagon and epinephrine Inhibited by insulin
5. Glycogen synthase is the key enzyme which is phosphorylated in active form. Glycogen phosphorylase is the key enzyme that is phosphorylated in its active form.

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Q. if glycogen is converted into glucose through glycogenolysis , then why does glucose again forms back into glycogen through glycogenesis?

The hormone which regulates the amount of glucose in the blood by converting excess of glucose into glycogen (glycogenesis) __(1)__. The hormone which regulates glucose in the blood by converting glycogen (glycogenolysis) back to glucose whenever required is __(2)__.

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S.no	Glycogenesis	Glycogenolysis
1.	The process takes place in the cells of muscle and liver.	The process takes place in the cells of the liver and muscle in reaction to neural and hormonal signals
2.	There is a requirement of 1 ATP (adenosine triphosphate) for any unit of glucose supplemented into the polymeric branched composition of glycogen at the time of glycogen synthesis.	It generates much more energy.
3.	Glycogenesis decreases the blood sugar level to normal.	Glycogenolysis increases the blood sugar level.
4.	Inhibited by glucagon and epinephrine	Inhibited by insulin
5.	Glycogen synthase is the key enzyme which is phosphorylated in active form.	Glycogen phosphorylase is the key enzyme that is phosphorylated in its active form.