What is the difference between ligase and lyase?

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Solution

Ligase: Ligase is the enzyme which ligate or bind two molecules together.
Lyase: Lyase is the enzyme which lyses or breaks a bond or molecule.
Ligase
Lyase
1.These are the enzymes which bind two molecules by forming new bond. 1.These are the enzymes which catalyzes the reactions involving the bond breaking.
2.These enzymes are involved in hydrolytic reactions. 2.These enzymes are involved in elimination reactions.
3.Two substrates are present in the reaction. 3. A single substrate is present in the reaction.

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Identify the correct set of enzymes by examining their action on substrates
I. $A H + B \to A + B H (N A D H)$
II. Transfers functional group and includes 'Kinases'.
III. $A - B + H_{2} O \to A - O H + B - H$
IV. Breaks bonds without using water (formation of double bonds).
V. Conversion of compounds into its isomer $A - B \to B - A$

VI. Joins different compounds. $A B + C \to A B - C$

What is the difference between DNA polymerase and DNA ligase?

Q. Match and find the correct option.

$(a)$	Oxidoreductases	$(i)$	Linking of the compounds
$(b)$	Isomerases	$(i i)$	Removal of group from substrate
$(c)$	Ligases	$(i i i)$	Interconversion of isomers
$(d)$	Lyases	$(i v)$	Dehydrogenases
		$(v)$	Hydrolysis

Q. Match the terms to these definitions
Cofactor, coenzyme, holoenzyme, apoenzyme, ligases, lyases, transferases, isozymes, zymogens, competitive inhibitor, non-competitive inhibitor, activation energy
..........enzymes which catalyse the linking together of compounds utilising the energy from ATP

Q. Match the following list and choose the correct combination.

List-A	List-B
(A) Oxidoreductases	(i) Linking of two compounds
(B) Isomerase	(ii) Removal of groups from substrates
(C) Ligases	(iii) Inter conversion of isomers
(D) Lyases	(iv) Dehydrogenation
	(v) Hydrolysis

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Ligase	Lyase
1.These are the enzymes which bind two molecules by forming new bond.	1.These are the enzymes which catalyzes the reactions involving the bond breaking.
2.These enzymes are involved in hydrolytic reactions.	2.These enzymes are involved in elimination reactions.
3.Two substrates are present in the reaction.	3. A single substrate is present in the reaction.