What is the difference between monocistronic and polycistronic?
Mono-cistronic mRNA: Mono-cistron means one cistron within a transcriptional unit, which means that it contains only one structural gene encoding a single polypeptide chain. Each gene contains a separate promoter region.
Polycistronic mRNA: Poly-cistron mRNA is an mRNA that encodes multiple proteins and is characteristic of many bacterial and chloroplast mRNAs.
Difference between monocistronic and polycistronic:
Monocistronic mRNA | Polycistronic mRNA |
1. Monocistron mRNA refers to mRNA with a single cistron. | 1. Polycistron mRNA refers to mRNA with two or more cistrons. |
2. Monocistron mRNA is found in eukaryotes. | 2. Polycistron mRNA is found in prokaryotes. |
3. Most mRNAs are monocistronic, but some are polycistrons. Open reading frame Monocistron mRNA is composed of a single open reading frame. | 3. Polycistron mRNA is composed of multiple open reading frames. |
4. Transcription of genes produces monocistronic mRNA. | 4. Transcription of operons produces polycistron mRNA. |
5. Monocistron mRNA can produce a single protein. | 5. Polycistron mRNA can produce multiple proteins. |