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What is the difference between monocistronic and polycistronic?


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Solution

Mono-cistronic mRNA: Mono-cistron means one cistron within a transcriptional unit, which means that it contains only one structural gene encoding a single polypeptide chain. Each gene contains a separate promoter region.

Polycistronic mRNA: Poly-cistron mRNA is an mRNA that encodes multiple proteins and is characteristic of many bacterial and chloroplast mRNAs.

Difference between monocistronic and polycistronic:

Monocistronic mRNAPolycistronic mRNA
1. Monocistron mRNA refers to mRNA with a single cistron.1. Polycistron mRNA refers to mRNA with two or more cistrons.
2. Monocistron mRNA is found in eukaryotes. 2. Polycistron mRNA is found in prokaryotes.

3. Most mRNAs are monocistronic, but some are polycistrons.

Open reading frame Monocistron mRNA is composed of a single open reading frame.

3. Polycistron mRNA is composed of multiple open reading frames.
4. Transcription of genes produces monocistronic mRNA.4. Transcription of operons produces polycistron mRNA.
5. Monocistron mRNA can produce a single protein.5. Polycistron mRNA can produce multiple proteins.

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