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Question

What is the difference between NADH and FADH2?


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Solution

FADH2 (reduced Flavin adenine dinucleotide – FAD): Flavin adenine dinucleotide is a redox-active coenzyme that is associated with a variety of proteins and is involved in several enzymatic reactions in metabolism. Flavoproteins are proteins that contain flavin groups that can take the form of FAD or flavin mononucleotides.

NADH (reduced Nicotinamide adenine dinucleotide – NAD): This chemical is naturally occurring in the body and plays a role in the chemical processes that generate energy.

Difference between NADH and FADH2:

NADHFADH2
Full-form: NADH (reduced Nicotinamide adenine dinucleotide – NAD).Full-form: FADH2 (reduced Flavin adenine dinucleotide – FAD).
ATP produced: By oxidative phosphorylation, NADH generates three ATP molecules.ATP produced: By oxidative phosphorylation, FADH2 generates two.
Complex in ETS: In the ETS, NADH transmits electrons to complex I.Complex in ETS: In the ETS, FADH2 transports electrons to complex II.

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