Question

What is the difference between nucleosomes and chromatin?

Answer 1

Nucleosomes:

1. Nucleosomes are structures formed by wrapping up negatively charged DNA on positively charged histone octamers.
2. Histones are positively charged basic proteins used for packaging DNA helix.
3. Histones are rich in basic amino acids such as lysine and Arginine.

Chromatin:

Chromatin is a bead on a string-like structure formed by repeating units of nucleosomes.

Nucleosomes	Chromatin
Nucleosomes are structures formed by wrapping up of DNA on histone octamers.	Chromatin are thread-like stained bodies with repeating units of nucleosomes.
2. A typical nucleosome consists of 200 base pairs.	2. On viewing under a microscope, nucleosomes appear as beads on a string.