Question

What is the effect fo denaturation on the structure of proteins?

Answer 1

As a result of denaturation, globules get unfolded and helixes get uncoiled. Secondary and tertiary structures of protein are destroyed, but the primary structures remain unaltered. It can be said that during denaturation, secondary and tertiary-structure proteins get converted into primary-structured proteins. Also, as the secondary and tertiary structures of a protein are destroyed, the enzyme loses its activity.

For example coagulation of egg white on boiling, curdling of milk due to bacterial action.