Question

What is the function of Leydig Cells?

Answer 1

Leydig cells:

1. Leydig cells also known as interstitial cells of Leydig are found adjacent to the seminiferous tubules in the testicle.
2. They produce testosterone in the presence of a luteinizing hormone (LH).
3. Leydig cells are polyhedral in shape and display a large prominent nucleus, an eosinophilic cytoplasm, and numerous lipid-filled vesicles.

The function of Leydig cells are:

1. Leydig cells release a class of hormones is called androgens (19- carbon steroids)
2. And they secrete testosterone, androstenedione, and dehydroepiandrosterone (DHEA) when stimulated by the pituitary hormone luteinizing hormone (LH).
3. LH increases cholesterol desmolase activity an enzyme associated with the conversion of cholesterol to pregnenolone, leading to testosterone synthesis by Leydig cells.