The correct option is B Release the synthesized polypeptide chain from ribosomes
A nonsense mutation is the substitution of a single base pair that leads to the appearance of a stop codon where previously there was a codon specifying an amino acid. The presence of this premature stop codon results in the production of a shortened, and likely nonfunctional, protein.
The function of non-sense codons is to terminate the message of a gene controlled protein synthesis. The three stop codons have been given names - UAG is amber, UGA is opal, and UAA is ochre.Stop codons are also called "termination" or "nonsense" codons. They signal the release of the nascent polypeptide from the ribosome because there is no cognate tRNA that has anticodons complementary to these stop signals, and so a release factor binds to the ribosome instead.
Hence, the correct answer is B.