Question

What is the function of secretin?

Answer 1

Secretin:

1. Secretin is a hormone that modifies the environment of the duodenum by controlling secretions in the stomach, pancreas, and liver.
2. It is a peptide hormone generated in the duodenum's S cells, which are found in the intestinal glands.

The function of secretin:

1. Secretin aids in the regulation of the pH of the duodenum to a more neutral to basic condition.
2. Secretin suppresses the release of gastric acid from the parietal cells of the stomach when it is no longer necessary.
3. Secretin works by boosting the synthesis of several digestive chemicals and enzymes that aid in digestion and absorption.
4. Secretin hormone from pancreatic ductal cells stimulates bicarbonate production.
5. Secretin also stimulates the liver to produce bile, which aids in the emulsification of dietary lipids in the duodenum.
6. The secretin hormone also regulates biliary alkalinization.
7. Secretion regulates the overall water equilibrium of the organism.
8. Secretin is vital in osmoregulation, which is the active regulation of an organism's body fluid osmotic pressure through working on the hypothalamus, pituitary gland, and kidneys.
9. In addition to secretin, the duodenum produces cholecystokinin (CCK), a hormone that induces gallbladder contraction and allows for the transport of stored bile.
10. Secretin hormone regulates water and electrolyte transport in epididymal epithelial cells, liver cholangiocytes, and pancreatic duct cells.
11. It is essential in the vasopressin-independent control of renal water reabsorption in the kidneys.