Question

What is the genetic disorder in which an individual has an overall masculine development, gynaecomastia and is sterile?

• A. Down's syndrome
• B. Turner's syndrome
• C. Klinefelter's syndrome
• D. Edward's syndrome

Answer 1

The correct option is C Klinefelter's syndrome

Klinefelter’s syndrome is a chromosomal disorder characterised by the presence of an extra X chromosome in the human males and hence the affected individuals have three sex chromosomes (XXY).

This condition is termed as trisomy of sex chromosomes.

The affected individuals display overall masculine development, however, the feminine characteristics like development of breast, i.e., gynecomastia are also seen. The affected individuals are sterile.

Down’s syndrome is a chromosomal disorder which is characterized by the trisomy of the 2st chromosome. The affected individuals have a short stature with rounded head, furrowed tongue, wide palm with distinct palm crease and retarded physical, mental and psychomotor development.

Turner’s syndrome is a chromosomal disorder in human beings characterized by the absence of one of the X chromosomes in females. Normal females have two X chromosomes. The affected females are sterile with rudimentary ovaries and lack secondary sexual characters.

Edwards syndrome, a chromosomal disorder which is characterized by the trisomic condition of chromosome 18. The affected individuals have small and abnormally shaped head and jaws, arched spine, and birth defects in many organs.