The correct option is A Human RBCs are non-nucleated
Main difference in human and frog RBC is human RBC are non-nucleated. Humans don't have a nucleus in their red blood cells, because they need more oxygen than frogs, so their red blood cells eliminated the nucleus to fit more oxygen in. Frogs can breathe under water and in air, so they don't need much oxygen, so their red blood cells didn't eliminate the nucleus. Hence, option A is correct.