In infected person. HIV enters into macrophages where virus is
replicated and gets incorporated with host cell's DNA with the help of
enzyme RNA transcriptase. Infected host cells produce virus particles so
that host's macrophages acts as HIV factors. At the same time, HIV
enters into helps T−lymphocytes(TH) and replicates to form
progeny virus. They again attack blood and helper T−lymphocytes.
This disease is T-helper leads to deficient immunity in infected person.