The nucleus is an organelle found in most eukaryotic cells, the exception being red blood cells. In animal cells it is both the largest and stiffest organelle and is easily identifiable by light microscopy. The average mammalian nucleus has a diameter of ~6µm and occupies about 10% of the total cell volume.
The nucleus consists of the following main parts: (1) Nucleolemma or nuclear membrane (karyotheca) (2) Nuclear sap or karyolymph or nucleoplasm (3) Chromatin network or fibres (4) Nucleolus (5) Endosomes
Two copies of chromosome 1, one copyinherited from each parent, form one of the pairs. Chromosome 1 is the largest human chromosome, spanning about 249 million DNA building blocks (base pairs) and representing approximately 8 percent of the total DNA in cells.