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Question

What is the optimal pH of pepsin?


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Solution

Pepsin:

  1. Pepsin is an enzyme produced by the stomach glands.
  2. Pepsin is a proteolytic enzyme generated by chief cells, which are specialised cells in the stomach.

Function of pepsin:

  1. It is a strong enzyme found in gastric juice that aids in protein digestion.
  2. Pepsin aids in protein digestion by turning it into peptides.
  3. Because of the presence of hydrochloric acid, pepsin becomes active or works.

pH of pepsin:

  1. The parietal cells in the stomach lining release hydrochloric acid, which lowers the stomach's pH.
  2. Pepsin is activated by a low pH (1.5 to 2).
  3. Pepsin works best at a pH of 1.8, which is very acidic.
  4. Pepsin, the stomach protease, is usually thought to have little action at pH 4.

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