What is the pathogenesis of AIDS virus? [5 MARKS]
What is the pathogenesis of AIDS virus? [5 MARKS]
Reason out: 5 Marks
The main cellular target of HIV is a special class of white blood cells critical to the immune system known as Helper T lymphocytes, or Helper T cells.
Helper T cells are also called CD4+ T cells because they have on their surfaces a protein called CD4.
Helper T cells play a central role in normal immune responses by producing factors that activate virtually all the other immune system cells.
These include B lymphocytes, which produce antibodies needed to fight infection; cytotoxic T lymphocytes, which kill cells infected with a virus; and macrophages and other effector cells, which attack invading pathogens. AIDS results from the loss of most of the helper T cells in the body thus weakening immunity.
Reason out: 5 Marks
The main cellular target of HIV is a special class of white blood cells critical to the immune system known as Helper T lymphocytes, or Helper T cells.
Helper T cells are also called CD4+ T cells because they have on their surfaces a protein called CD4.
Helper T cells play a central role in normal immune responses by producing factors that activate virtually all the other immune system cells.
These include B lymphocytes, which produce antibodies needed to fight infection; cytotoxic T lymphocytes, which kill cells infected with a virus; and macrophages and other effector cells, which attack invading pathogens. AIDS results from the loss of most of the helper T cells in the body thus weakening immunity.
