Answer :-
Pesticides/heavy metals enter the soil or are washed away by run off water to surface water bodies such as lakes, streams, rivers. From soil or water these pesticides/heavy metals then enter the food chain via the producers. At each trophic level, their concentration goes on increasing. This phenomenon of increase in concentration of harmful non-biodegradable chemical substances in the body of living organisms at each trophic level of the food chain is called biomagnification.
For example, biomagnification of mercury in the fishes through a food chain results in Minamata disease in fish-eating human populations of the region.