Virus infected cells secrete proteins called interferons which protect non infected cells from further viral infection. They are usually produced by leukocytes and play major roles in the immune system.
The
interferons have potential medical applications due to their antiviral and
anti-proliferatory activities as well as their ability in regulation of immune
and inflammatory responses within the body. The production of interferons in
minute quantities remained a drawback in their therapeutic applications. Hence,
various techniques for their isolation from different sources were studied. The recombinant DNA technology has helped in the large-scale
production of interferons for meeting the different medical needs by the
recombinant expression of the interferons in the microbial organisms.