What is the reason for shearing of the cell when it is put in a high pressure homogenization
A
The suspension liquid
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B
The small orifice
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C
High pressure
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D
A combination of high pressure and small orifice
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Solution
The correct option is D A combination of high pressure and small orifice High pressure homogenization involves pushing the cells through a small orifice under high pressure. The high pressure on the cells that is moving out through a smalll orifice creates a shearing effect that can break the cell wall.