Question

What is the role of acrosome reacting ability in assisted reproductive technology?

Answer 1

Acrosome:

1. Acrosome is present at the anterior end of the elongated nucleus, present in the sperm head as the cap-like structure.
2. It is derived from the Golgi apparatus. The acrosome contains proteolytic enzymes such as hyaluronidase and acrosin.

Role of acrosome:

1. The acrosome reaction is the last step that sperm experience before it is finally able to fertilize.
2. The acrosome reaction permits the penetration of the sperm of the ZP and union to the lemma.
3. Finding the acrosome reacting ability is vital in the therapeutic and diagnostic approach to couples who undergo conventional assisted reproductive technology treatments.
4. In the event of a poor acrosome reaction, ICSI therapy can be recommended.
5. As most of the centers depict ICSI as the primary ART technique, the AR assay is hardly utilized.