Question

What is the role of pyridine in the given chemical reaction?

• A. It act as nucleophile
• B. It shift equilibrium toward forward reaction
• C. It removes $HCl$ formed in the reaction
• D. It abstract $\alpha$-hydrogen from amines

Answer 1

Answer: (B), (C)

It removes $HCl$ formed in the reaction

Reaction of amines with acyl chloride in presence of base is the Schotten-Baumann reaction.
Here, the base used should be strong than amines. Pyridine is used in the reaction to removes $HCl$/acid formed in the reaction. By Le-chateliers principle, removal of acid in product side will shift the equilibrium toward the product side.
Thus, statements (b) and (c) are correct.