Question

What is the role of tight junctions?

Answer 1

Role of tight junction:

1. Tight junctions form the continuous intercellular barrier between epithelial cells, which is required to separate tissue spaces and regulate the selective movement of solutes across the epithelium.
2. It supports the maintenance of cell polarity by restricting intermixing of apical and basolateral transmembrane components.
3. Tight junctions also serve as a structural support mechanism that helps keep the epithelium together.
4. It helps stop particles from leaking across tissues.