Question

What is the significance of progesterone-estrogen combination as a contraceptive measure?

Answer 1

Contraceptives:

Contraceptives are devices, methods or drugs that serve the function of preventing pregnancy.

Progesterone and estrogen combination :

Progesterone and estrogen are steroid hormones. Progesterone is commonly produced by the adrenal cortex as well as the gonads and estrogen is produced by the ovaries. Progesterone and estrogen play a pivotal role in the regulation of mammalian reproduction.
Progesterone and estrogen combination is used in various contraceptive methods like pills. Examples include Mala-D.

Significance of progesterone-estrogen combination:

$\bullet$ They work by inhibiting ovulation (releasing of secondary oocytes) or by changing the quality of the mucus present in the cervix leading to inhibition of sperm penetration.

$\bullet$ They inhibit implantation, the attachment of embryos to the uterine wall.

Summary

Progesterone and estrogen combination:

Progesterone and estrogen combination is used in various contraceptive methods like pills.

Mechanism of action :

It prevents pregnancy by inhibiting ovulation or by changing the quality of the mucus present in the cervix leading to inhibition of sperm penetration. Also, they inhibit implantation, the attachment of embryos to the uterine wall.