Biocontrol Agents (or) biological control agents. The natural enemies like parasitism, predation and other mechanisms for controlling the plant pests are referred as a biocontrol agent. They play an important role in controlling the plant pests like nematodes weeds, insects, and mites. Baculoviruses are insect pathogenic viruses that are used for pest insect control and as tools to produce recombinant proteins. Numerous studies show that both natural baculoviruses and genetically modified (GM) baculoviruses hold clear and substantial benefits for crop protection.