The correct option is B Invention of printing press led to the printing of multiple copies of books.
In 1455 CE, Gutenberg from Germany invented the printing press. Multiple copies of various books were printed, and this enabled the rapid spread of knowledge. When Ottoman Turks invaded Constantinople in 1453 CE, the scholars from Constantinople took abode in Italy. The kings and popes patronised these scholars, and this also led to the spread of knowledge in Italy. Thus, Italy became the Land of the Renaissance.