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Question

What particular aspect of DNA replication causes the leading strand to be constructed more quickly than the lagging strand?
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A
DNA replication requires primase to assemble a primer.
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B
To begin replication, the origin of replication must first be opened by initiator proteins.
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C
During replication, DNA can only be built in a 5' to 3' direction.
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D
DNA replication is a semiconservative process that depends on complementary base pairing.
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Solution

The correct option is C During replication, DNA can only be built in a 5' to 3' direction.
Synthesis of RNA from DNA is known as transcription.
One of the two strands of DNA takes part during transcription. The main enzyme which is responsible for this is the RNA polymerase II enzyme that synthesises the hn RNA the main factor.
RNA polymerase enzyme works in the direction 5'-3', therefore, the part of the DNA that has the polarity 3'-5' is known as the template or master strand because the DNA will be formed from that strand.
The other stand which does not take part in the transcription is known as the coding strand or the lagging strand.
So the correct answer is 'During DNA replication, DNA can only built in a 5' to 3' direction.



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