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Question

What triggers gastrin?


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Solution

Gastrin:

  1. A peptide hormone produced by cells of the upper intestine stimulates the secretion of gastric juice.
  2. Gastrin is secreted into the stomach as a result of food items, peptides, calcium, amino acids, and an increase in pH.

Gastrin secretion is triggered by:

  1. The secretion of gastrin is also stimulated by the intake of antacid medications which increases the pH of the stomach and reduces the acid levels in the stomach.
  2. High levels of gastrin hormone are associated with Zollinger-Ellison syndrome, a syndrome that is caused by the gastrin-secreting tumor in the digestive system.
  3. Low levels of gastrin in the stomach can increase the risk of infections in the digestive system and also reduces the ability of the stomach to absorb nutrients.

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