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Question
What will be the product of the following reaction:
What will be the product of the following reaction:
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Solution
The correct option is D
The end product of the synthetic sequence is isoindolin-1-one. The first step is Hoffmann bromamide degradation, in which an amide is treated with bromine and aqueous or alcoholic sodium hydroxide to form a primary amine. The second step is intramolecular amide formation.
The end product of the synthetic sequence is isoindolin-1-one. The first step is Hoffmann bromamide degradation, in which an amide is treated with bromine and aqueous or alcoholic sodium hydroxide to form a primary amine. The second step is intramolecular amide formation.
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