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Question

What would account for increase urine production as a result of drinking alcoholic beverages?

A
Increased aldosterone production
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B
Increased blood pressure
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C
Inhibition of antidiuretic hormone secretion (ADH)
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D
Increased reabsorption of water in the proximal tubule
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Solution

The correct option is C Inhibition of antidiuretic hormone secretion (ADH)
Increased urine flow results from alcohol’s acute inhibition of the release of antidiuretic hormone (ADH), that normally promotes the formation of concentrated urine by inducing the kidneys to conserve fluids. In the absence of ADH, segments of the kidney’s tubule system become impermeable to water, thus preventing it from being reabsorbed into the body. Under these conditions, the urine formed is dilute and electrolyte concentration in the blood simultaneously rises.

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